主要围绕重要高致病性病毒，包括克里米亚-刚果出血热病毒CCHFV、新冠病SARS-CoV-2、脾传脑炎病毒TBEV等开展了致病机制研究及小分子药物和单抗研发。在新冠病毒、高致病性布尼亚病毒CCHFV及大DNA病毒感染机制及药物研究中取得了一系列重要研究成果。以第一作者/通讯作者（含共同）在Cell Res、Nat Commun、Cell Discov、Adv Sci、JACS、PLoS Pathog、J Virol、Antiviral Res等国际期刊上共发表论文70余篇。
Hu H, Vlak JM, Hu Z, Wang M*. Discovery of novel non-retroviral endogenous viral elements reveals their long-term integration history in spiders. Nat Commun (15.7). 2025; 16(1):6006.
Li L, Liu Y, Rao J, Hu H, Liu J, Wang X, Li J, Hu Z, Wang M*. Mucin-like protein of Crimean-Congo hemorrhagic fever virus is a key virulence factor and a potent target for developing novel attenuated vaccine. Cell Res (36.5). 2025; 35(7):524-527.
Hu H#, Leng C#, Shu Y#, Peng L, Wu F, Liu J, Zhang X, Zhou W, Xiao Q, Li Y, Wu B, Shen J, Li J, Gong R, Yan B, Deng F, Hu Z, Cao S*, Wang M*. Structural insights into hybridoma-derived neutralizing monoclonal antibodies against Omicron BA.5 and XBB.1.16 variants of SARS-CoV-2. J Virol (4.0). 2025; 99(2):e0130724.
Liu K#, Li L#, Liu Y, Wang X, Liu J, Li J, Deng F, Zhang R, Zhou Y, Hu Z*, Zhong W*, Wang M*, Guo C*. Discovery of baloxavir sodium as a novel anti-CCHFV inhibitor: Biological evaluation of in vitro and in vivo. Antiviral Res (5.0). 2024; 227:105890.
Li L#, Chong T#, Peng L#, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S*, Wang M*. Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus; PLoS Pathog (5.5). 2024; 20(2):e1011948.
Yin M #, Kuang W #, Wang Q, Wang X, Yuan C, Lin Z, Zhang H, Deng F, Jiang H, Gong P*, Zou Z*, Hu Z*, Wang M* . Dual roles and evolutionary implications of P26/poxin in antagonizing intracellular cGAS-STING and extracellular melanization immunity. Nat Commun (15.7). 2022; 13(1):6934. doi: 10.1038/s41467-022-34761-0.
Wang M#, Cao R#, Zhang L#, Yang X#, Liu J, Xu M, Shi Z, Hu Z*, Zhong W*, Xiao G*. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res (36.5). 2020; 30(3):269-271.
Liu J#, Li Y#, Liu L#, Hu X, Wang X, Hu H, Hu Z, Zhou Y*, Wang M* . Infection of human sweat glands by SARS-CoV-2. Cell Discov (14.8). 2020; 6(1):84.
Wang X#, Cao R#, Zhang H#, Liu J, Xu M, Hu H, Li Y, Zhao L, Li W, Sun X, Yang X, Shi Z, Deng F, Hu Z*, Zhong W*, Wang M*. The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro. Cell Discov (14.8). 2020; 6:28.
Liu J#, Cao R#, Xu M#, Wang X, Zhang H, Hu H, Li Y, Hu Z*, Zhong W*, Wang M* . Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro. Cell Discov (14.8). 2020; 6:16.
